{"id":493,"date":"2020-10-02T20:24:42","date_gmt":"2020-10-02T12:24:42","guid":{"rendered":"http:\/\/www.hdygyy.com.cn\/?p=493"},"modified":"2020-11-22T11:27:22","modified_gmt":"2020-11-22T03:27:22","slug":"%e5%85%8b%e7%bd%97%e6%81%a9%e7%97%85%e7%9a%84%e6%88%90%e5%9b%a0","status":"publish","type":"post","link":"http:\/\/www.scd520.com\/?p=493","title":{"rendered":"\u514b\u7f57\u6069\u75c5\u7684\u6210\u56e0"},"content":{"rendered":"<p>\u5bf9\u4e8e\u514b\u7f57\u6069\u6c0f\u75c5\uff0c\u79d1\u5b66\u5bb6\u5c1a\u4e0d\u786e\u5b9a\u786e\u5207\u539f\u56e0\u662f\u4ec0\u4e48\u3002\u7136\u800c\uff0c\u5173\u4e8e\u53ef\u80fd\u5bfc\u81f4\u514b\u7f57\u6069\u6c0f\u75c5\u548c\u5176\u4ed6\u5f62\u5f0f\u7684\u708e\u75c7\u6027\u80a0\u75c5\uff08IBD\uff09\u539f\u56e0\u7684\u7406\u8bba\u6b63\u5728\u7f29\u5c0f\uff0c\u76ee\u524d\u7684\u60f3\u6cd5\u662f\uff0c\u5b83\u53ef\u80fd\u662f\u591a\u79cd\u56e0\u7d20\u7684\u590d\u6742\u76f8\u4e92\u4f5c\u7528\uff0c\u5305\u62ec\u57fa\u56e0\uff0c\u514d\u75ab\u7cfb\u7edf\u53c2\u4e0e\u548c\u73af\u5883\u89e6\u53d1\u56e0\u7d20\u3002\uff08\u8be6\u89c1\uff1a<u><a class=\" wrap external\" href=\"https:\/\/link.zhihu.com\/?target=https%3A\/\/doi.org\/10.1007\/s00535-018-1479-6\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" data-za-detail-view-id=\"1043\">\u6cbb\u7597\u514b\u7f57\u6069\u75c5\u7684\u6700\u65b0\u6280\u672f<\/a><\/u>\u3002J\u80c3\u80a0\u30022018; 53\uff089\uff09\uff1a989-998\u3002doi\uff1a10.1007 \/ s00535-018-1479-6\uff09<\/p>\n<h2><b>\u57fa\u56e0<\/b><\/h2>\n<p>\u5f04\u6e05\u695a\u514b\u7f57\u6069\u75c5\u5982\u4f55\u9057\u4f20\u7684\u786e\u5207\u6027\u8d28\u662f\u9700\u8981\u65f6\u95f4\u7684\uff0c\u56e0\u4e3a\u5c3d\u7ba1\u4e00\u6bb5\u65f6\u95f4\u4ee5\u6765\u4eba\u4eec\u5df2\u7ecf\u77e5\u9053\u514b\u7f57\u6069\u75c5\u662f \u201c\u5bb6\u5ead\u4f20\u67d3\u75c5 \u201d\uff0c\u4f46\u8fd8\u4e0d\u6e05\u695a\u8fd9\u79cd\u75c5\u662f\u5982\u4f55\u53d1\u751f\u7684\u3002<\/p>\n<p>\u79d1\u5b66\u5bb6\u73b0\u5df2\u9274\u5b9a\u51fa\u7ea6200\u4e2a\u57fa\u56e0\uff0c\u8fd9\u4e9b\u57fa\u56e0\u53ef\u80fd\u4e0e\u514b\u7f57\u6069\u6c0f\u75c5\u6709\u5173\u3002\uff08\u8be6\u89c1\uff1a\u9057\u4f20\u5b66\u5bb6\u5ead\u53c2\u8003\u3002<u><a class=\"internal\" href=\"https:\/\/zhuanlan.zhihu.com\/p\/248060341\/edit#genes\" data-za-detail-view-id=\"1043\">\u514b\u7f57\u6069\u75c5<\/a><\/u>\uff09<\/p>\n<p>\u60a3\u6709\u514b\u7f57\u6069\u75c5\u7684\u4eba\u4e2d\u67092\uff05\u523014\uff05\u7684\u4eba\u90fd\u6709\u4eb2\u621a\u4e5f\u60a3\u6709\u8fd9\u79cd\u75be\u75c5\uff0c\u8fd9\u610f\u5473\u7740\u5927\u591a\u6570\u60a3\u6709IBD\u7684\u4eba\u5b9e\u9645\u4e0a\u6ca1\u6709\u4eb2\u621a\u60a3\u6709\u8fd9\u79cd\u75be\u75c5\u3002<\/p>\n<p>\u4f46\u662f\uff0c\u5bf9\u4e8e\u5bb6\u5ead\u6210\u5458\u60a3\u6709IBD\u7684\u4eba\uff0c\u60a3\u8be5\u75c5\u7684\u98ce\u9669\u4f1a\u589e\u52a0\u3002\u4eba\u4eec\u8ba4\u4e3a\uff0c\u4ec5\u4ec5\u62e5\u6709\u57fa\u56e0\u7684\u56e0\u7d20\u4e0d\u8db3\u4ee5\u53d1\u5c55\u6210\u514b\u7f57\u6069\u6c0f\u75c5\uff0c\u8fd8\u5fc5\u987b\u6709\u4e00\u4e2a\u6216\u591a\u4e2a\u201c\u89e6\u53d1\u5668\u201d\u5bfc\u81f4IBD\u7684\u53d1\u5c55\u3002\u56e0\u4e3a\u5e76\u975e\u6bcf\u4e2a\u643a\u5e26\u4e0e\u514b\u7f57\u6069\u75c5\u76f8\u5173\u57fa\u56e0\u7684\u4eba\u6700\u7ec8\u90fd\u4f1a\u60a3\u75c5\uff0c\u6240\u4ee5\u53ef\u4ee5\u7406\u89e3\uff0c\u75c5\u56e0\u4e0d\u4ec5\u5305\u62ec\u9057\u4f20\u56e0\u7d20\uff0c\u8fd8\u6709\u5176\u4ed6\u65b9\u9762\u7684\u539f\u56e0\u3002<\/p>\n<h2><b>\u81ea\u8eab\u514d\u75ab\u53cd\u5e94<\/b><\/h2>\n<p>\u514b\u7f57\u6069\u6c0f\u75c5\u901a\u5e38\u88ab\u63cf\u8ff0\u4e3a\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u6216\u8005\u6700\u8fd1\u88ab\u79f0\u4e3a\u514d\u75ab\u4ecb\u5bfc\u7684\u75be\u75c5\u3002\u8fd9\u662f\u56e0\u4e3a\u4eba\u4eec\u8ba4\u4e3a\u8be5\u75be\u75c5\u5b9e\u9645\u4e0a\u6e90\u4e8e\u514d\u75ab\u7cfb\u7edf\u7684\u95ee\u9898\u3002<\/p>\n<p>\u7531\u4e8e\u79d1\u5b66\u5bb6\u5c1a\u4e0d\u6e05\u695a\u7684\u67d0\u4e9b\u539f\u56e0\uff0c\u53ef\u80fd\u4f1a\u89e6\u53d1\u514d\u75ab\u7cfb\u7edf\u6765\u201c\u653b\u51fb\u201d\u6d88\u5316\u7cfb\u7edf\u7684\u5065\u5eb7\u90e8\u5206\u3002\u8fd9\u5c31\u662f\u7ecf\u5e38\u7528\u6291\u5236\u514d\u75ab\u7cfb\u7edf\u7684\u836f\u7269\u6765\u6cbb\u7597\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u539f\u56e0\u3002\u5f53\u514d\u75ab\u7cfb\u7edf\u53d7\u5230\u6291\u5236\u65f6\uff0c\u5b83\u53ef\u4ee5\u51cf\u5c11\u8fc7\u5ea6\u6d3b\u8dc3\u514d\u75ab\u7cfb\u7edf\u5bf9\u6d88\u5316\u7cfb\u7edf\u8fdb\u884c\u653b\u51fb\u3002<\/p>\n<p>\u514d\u75ab\u7cfb\u7edf\u4e2d\u7684\u5931\u706b\u53ef\u80fd\u6765\u81ea\u67d0\u79cd\u8fc7\u654f\u53cd\u5e94\uff0c\u5bfc\u81f4\u5927\u91cf\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u91ca\u653e\u3002 \u55dc\u9178\u6027\u7c92\u7ec6\u80de\u662f\u62b5\u6297\u8fc7\u654f\u53cd\u5e94\u7684\u7ec6\u80de\u3002\u8fd9\u6837\u505a\u4f1a\u91ca\u653e\u51fa\u6709\u6bd2\u7684\u5316\u5408\u7269\u3002\u7814\u7a76\u8868\u660e\uff0c\u60a3\u6709\u514b\u7f57\u6069\u75c5\u7684\u4eba\u7684\u8840\u6db2\u548c\u7ec4\u7ec7\u4e2d\u8fc7\u91cf\u7684\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u4e4b\u95f4\u5b58\u5728\u5173\u8054\u3002\uff08\u8be6\u89c1\uff1a<a class=\" wrap external\" href=\"https:\/\/link.zhihu.com\/?target=https%3A\/\/doi.org\/10.1016\/j.crohns.2011.02.009\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" data-za-detail-view-id=\"1043\">\u55dc\u9178\u6027\u514b\u7f57\u6069\u91cd\u53e0\u6027\u7ed3\u80a0\u708e\u5e76\u6587\u732e<\/a>\u3002J\u514b\u7f57\u6069\u65af\u7ed3\u80a0\u708e\u30022011; 5\uff083\uff09\uff1a256-61\u3002doi\uff1a10.1016 \/ j.crohns.2011.02.009\uff09<\/p>\n<h2><b>\u73af\u5883\u89e6\u53d1\u56e0\u7d20<\/b><\/h2>\n<p>\u5373\u4f7f\u8003\u8651\u4e86\u9057\u4f20\u548c\u514d\u75ab\u7cfb\u7edf\u56e0\u7d20\uff0c\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u4fc3\u53d1\u56e0\u7d20\u4ecd\u53ef\u80fd\u8fd8\u6709\u66f4\u591a\u3002<\/p>\n<p>\u79d1\u5b66\u5bb6\u4eec\u8fd8\u8ba4\u4e3a\uff0c\u4e00\u79cd\u6216\u591a\u79cd\u73af\u5883\u56e0\u7d20\u53ef\u80fd\u4e0e\u514b\u7f57\u6069\u7684\u6210\u56e0\u6709\u5173\u3002<\/p>\n<p>\u76ee\u524d\u5c1a\u4e0d\u6e05\u695a\u8fd9\u4e9b\u89e6\u53d1\u56e0\u7d20\u4e2d\u6709\u591a\u5c11\u6216\u5b83\u4eec\u5982\u4f55\u4e0e\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u5176\u4ed6\u6f5c\u5728\u539f\u56e0\u76f8\u4e92\u4f5c\u7528\u3002\u6b63\u5728\u7814\u7a76\u7684\u4e00\u4e9b\u53ef\u80fd\u7684\u89e6\u53d1\u56e0\u7d20\u5305\u62ec\uff1a\uff08\u8be6\u89c1\uff1a<u><a class=\" wrap external\" href=\"https:\/\/link.zhihu.com\/?target=https%3A\/\/doi.org\/10.1016\/j.mayocp.2017.04.010\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" data-za-detail-view-id=\"1043\">\u514b\u7f57\u6069\u75c5\uff1a\u6d41\u884c\u75c5\u5b66\uff0c\u8bca\u65ad\u548c\u7ba1\u7406<\/a><\/u>\u3002\u6885\u5965\u8bca\u6240 2017; 92\uff087\uff09\uff1a1088-1103\u3002doi\uff1a10.1016 \/ j.mayocp.2017.04.010\uff09<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u62bd\u70df\u3002<\/b>\u9999\u70df\u4f1a\u4f7f\u514b\u7f57\u6069\u75c5\u6076\u5316\uff0c\u56e0\u6b64\u9f13\u52b1\u60a3\u6709\u8be5\u75c5\u7684\u4eba\u4e0d\u8981\u5438\u70df\u3002\u5f53\u524d\u5438\u70df\u6216\u8fc7\u53bb\u5438\u70df\u7684\u4eba\u60a3\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u98ce\u9669\u589e\u52a0\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u975e\u753e\u4f53\u6297\u708e\u836f\uff08NSAIDs\uff09\u3002<\/b>\u8fd9\u4e9b\u5e38\u89c1\u7684\u6b62\u75db\u836f\u53ef\u80fd\u4e0e\u514b\u7f57\u6069\u75c5\u53d1\u4f5c\u52a0\u5267\u6709\u5173\u3002\u76ee\u524d\u5c1a\u4e0d\u6e05\u695a\u5b83\u4eec\u5728\u75be\u75c5\u53d1\u5c55\u4e2d\u53ef\u80fd\u53d1\u6325\u7684\u4f5c\u7528\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u6297\u751f\u7d20\u3002<\/b>\u6709\u8bc1\u636e\u8868\u660e\uff0c\u5c24\u5176\u662f\u5728\u751f\u547d\u7684\u65e9\u671f\uff0c\u6297\u751f\u7d20\u7684\u4f7f\u7528\u53ef\u80fd\u4f1a\u5bfc\u81f4\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u53d1\u5c55\u3002\u5728\u67d0\u4e9b\u4eba\u4e2d\uff0c\u6297\u751f\u7d20\u4e5f\u4e0e\u75be\u75c5\u7684\u53d1\u4f5c\u6709\u5173\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u907f\u5b55\u836f\u3002<\/b>\u6709\u8bc1\u636e\u8868\u660e\uff0c\u907f\u5b55\u836f\uff08\u907f\u5b55\u836f\uff09\u53ef\u80fd\u4f1a\u589e\u52a0\u60a3\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u98ce\u9669\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u5730\u7406\u4f4d\u7f6e\u3002<\/b>\u514b\u7f57\u6069\u6c0f\u75c5\u5728\u5de5\u4e1a\u5316\u56fd\u5bb6\u4e2d\u66f4\u4e3a\u666e\u904d\uff0c\u5c24\u5176\u662f\u5728\u5317\u7f8e\u548c\u897f\u6b27\uff0c\u5c3d\u7ba1\u5728\u4e9a\u6d32\u548c\u5357\u7f8e\uff0c\u53d1\u75c5\u7387\u6b63\u5728\u4e0a\u5347\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5bf9\u4e8e\u514b\u7f57\u6069\u6c0f\u75c5\uff0c\u79d1\u5b66\u5bb6\u5c1a\u4e0d\u786e\u5b9a\u786e\u5207\u539f\u56e0\u662f\u4ec0\u4e48\u3002\u7136\u800c\uff0c\u5173\u4e8e\u53ef\u80fd\u5bfc\u81f4\u514b\u7f57\u6069\u6c0f\u75c5\u548c\u5176\u4ed6\u5f62\u5f0f\u7684\u708e\u75c7\u6027\u80a0\u75c5\uff08IBD\uff09\u539f\u56e0 &hellip;<\/p>\n","protected":false},"author":1,"featured_media":1266,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[32],"tags":[],"_links":{"self":[{"href":"http:\/\/www.scd520.com\/index.php?rest_route=\/wp\/v2\/posts\/493"}],"collection":[{"href":"http:\/\/www.scd520.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.scd520.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.scd520.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.scd520.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=493"}],"version-history":[{"count":1,"href":"http:\/\/www.scd520.com\/index.php?rest_route=\/wp\/v2\/posts\/493\/revisions"}],"predecessor-version":[{"id":1267,"href":"http:\/\/www.scd520.com\/index.php?rest_route=\/wp\/v2\/posts\/493\/revisions\/1267"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.scd520.com\/index.php?rest_route=\/wp\/v2\/media\/1266"}],"wp:attachment":[{"href":"http:\/\/www.scd520.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=493"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.scd520.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=493"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.scd520.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}